JAAPA CME Post-Test September 2024

Silicosis: No Longer Exclusively A Chronic Disease

Silicosis typically has been classified as a chronic disease that develops after at least 10 years of exposure to silica dust, and often is associated with miners and stone workers. As industries have changed over time, other types of workers (including those in artificial stonework, jewelry polishing, and denim production) have become exposed to high levels of silica, leading to the development of acute and accelerated silicosis. Acute silicosis can develop in as little as a few months, and accelerated silicosis can develop in as little as two years. No cure exists for any form of silicosis, and lung transplantation is the only lifesaving treatment. Primary care clinicians must understand when patients are at risk for developing silicosis and not assume that a short time of exposure precludes the development of silicosis.

Learning Objectives

At the conclusion of this activity, participants should be able to:
  • Identify all forms of silicosis and in what industries patients are at higher risk for developing silicosis
  • Describe why clinicians must elicit a complete and accurate occupational history to assess patient risks and avoid misdiagnosis
  • Explain why patient education is crucial to help patients avoid developing acute and accelerated silicosis

Serotonin Syndrome: A Rare Yet Crucial Diagnosis

Serotonin syndrome is a rare, life-threatening toxidrome caused by serotonergic agents. This syndrome classically presents with a combination of mental status changes, autonomic hyperactivity, and neuromuscular abnormalities. However, diagnosing the condition is difficult because of its variable symptoms at presentation. As a result, serotonin syndrome often is underreported, making it harder to understand, recognize, and treat. Patients with this condition may present to primary or urgent care or an ED, and may become acutely symptomatic during an inpatient admission. Clinicians must be able to identify at-risk patients and intervene to prevent potentially lethal complications.
 

Learning Objectives

At the conclusion of this activity, participants should be able to:
  • List the causes of serotonin syndrome
  • List risk factors for serotonin syndrome
  • Describe the most common signs and symptoms of serotonin syndrome
  • Describe acute management of serotonin syndrome
 

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