JAAPA CME Post-Test November 2023

A Review of Merkel Cell Carcinoma

Merkel cell carcinoma (MCC) is a rare and aggressive type of metastatic, nonmelanoma skin cancer derived from Merkel cells in the epidermis. MCC can be induced by sun exposure or via Merkel cell polyomavirus (MCV) gene expression. MCV is found in most patients with MCC and is associated with a lower recurrence rate of MCC. MCC has a wide range of clinical presentations that make diagnosis challenging. Histologic examination is performed using unique markers to differentiate it from other diagnoses. This activity reviews the pathogenesis, clinical presentation, histopathology, differential diagnosis, and treatment of MCC.

Learning Objectives

  • Describe the epidemiology and pathogenesis of MCC
  • Describe the clinical presentation of MCC
  • List the differential diagnosis of patients with suspected MCC
  • Describe the process for diagnosing MCC
  • List treatment options for patients with MCC

Screening and Therapeutic Recommendations For Patients With Alcohol Use Disorder

Alcohol use disorder (AUD) is the most prevalent substance use disorder worldwide. Early screening can identify patients at risk for developing AUD, creating opportunities for prevention and early intervention. This activity encourages the use of AUD screening tools, explores AUD treatments, and aims to equip clinicians with evidence-based strategies to prevent and manage AUD.

Learning Objectives

  • Define AUD
  • Discuss the screening modalities available to assist in the diagnosis of AUD
  • List the treatment options for patients diagnosed with AUD

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