Clinical Dialogue: Getting Ahead of Migraine: Best Practices for Migraine Treatment and Prevention

Migraine is a prevalent neurological disease, affecting 38 million adults in the U.S., or 13% of the population. This illness exacts a substantial toll on patients, compromising their ability to perform activities of daily living. More than 90% of individuals are unable to work or function normally during their migraine, and 53% have severe disability requiring restrictions in activity or bed rest. Migraine is a leading cause of both outpatient and emergency department visits and remains an important public health problem. Despite its prevalence and significant consequences, migraine remains underdiagnosed and undertreated. Lack of an accurate diagnosis can cause patients to become resigned to living with this condition, or can lead to inappropriate treatment due to mistaken diagnosis of another headache disorder. Therefore, it is incumbent on PAs to become skilled in the recognition of migraine to initiate treatment aimed at optimizing outcomes.

Learning Objectives

At the conclusion of this activity, the PA should be better able to: 

  • Use diagnostic criteria for diagnosing episodic and chronic migraine
  • Demonstrate appropriate utilization of pharmacologic treatment options for acute migraine
  • Compare the safety and efficacy data of newly approved acute migraine treatments
  • Demonstrate appropriate utilization of pharmacologic treatment options for migraine prevention
  • Compare the safety and efficacy data of newly approved migraine preventive treatments
  • Implement strategies to ensure optimal adherence to migraine therapies

Acknowledgement of Commercial Support


Supported by independent educational grants from AbbVie and Amgen, Inc.