Monograph: Individualized Management of Patients with T2DM and Comorbidities While Reducing Hypoglycemia Risk

Hypoglycemia remains the rate-limiting factor in the achievement of glycemic goals in patients with type 2 diabetes mellitus (T2DM) treated with pharmacotherapy. Unfortunately, hypoglycemia is common among patients with type 1 and type 2 diabetes mellitus and can have serious clinical consequences when not managed properly. According to national surveillance data, annual rates of severe hypoglycemic events are likely grossly underestimated, with self-reported severe events occurring in approximately 12% of patients annually. Given the potentially dangerous consequences of hypoglycemia, PAs must remain up to date on all aspects of T2DM management, especially in those with significant comorbid conditions.

Learning Objectives
At the conclusion of this activity, the PA should be better able to:
  • Identify risk factors and comorbid conditions that may increase the risk of hypoglycemia.
  • Choose individualized A1C treatment goals accordingly. 
  • Select newer treatment options with a low risk of hypoglycemia.
  • Use therapies that demonstrate cardiovascular and renal benefit in patients at heightened risk.